Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 12/20 | 0.60 |
| ▸ | CYSLTR1 | Q9Y271 | 12/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837811 | 1.00 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL7496760 | 0.83 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL7496756 | 0.83 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL27340570 | 0.82 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL9837337 | 0.81 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL9837331 | 0.81 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL10764144 | 0.81 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL10764142 | 0.81 | CYSLTR2 (0.64) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL7502713 | 0.80 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1KDM4ELMNARAB9A | |
| SCHEMBL7502719 | 0.80 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1KDM4ELMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | disclosed |