Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 14/20 | 0.65 |
| ▸ | CYSLTR1 | Q9Y271 | 14/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9837337 | 1.00 | CYSLTR2 (0.65) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL9836508 | 0.85 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL9836512 | 0.85 | CYSLTR2 (0.70) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL7496756 | 0.82 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL7496760 | 0.82 | CYSLTR2 (0.68) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL9837804 | 0.81 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL9837811 | 0.81 | CYSLTR2 (0.60) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL3627230 | 0.81 | KEAP1 (0.60) | KDM4EPKM | |
| SCHEMBL27340570 | 0.81 | CYSLTR2 (0.62) | CYSLTR2CYSLTR1KDM4ELMNANPC1 | |
| SCHEMBL7502719 | 0.79 | CYSLTR2 (0.63) | CYSLTR2CYSLTR1KDM4ELMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | claimed |
| EP-0219308-A2 | 2-Substituted quinolines | MERCK FROSST CANADA INC. (CA) | 1987-04-22 | — | — | EP | claimed |
| EP-0219308-B1 | 2-SUBSTITUTED QUINOLINES | MERCK FROSST CANADA INC. (CA) | 1991-10-23 | — | — | EP | disclosed |
| EP-0219308-A2 | 2-Substituted quinolines | MERCK FROSST CANADA INC. (CA) | 1987-04-22 | — | — | EP | disclosed |