Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3788786 | 0.92 | ACACB (0.55) | MMEACEITGB1ITGA4HPGD | |
| SCHEMBL3788780 | 0.92 | ACACB (0.55) | MMEACEITGB1ITGA4HPGD | |
| SCHEMBL26008175 | 0.86 | TAAR1 (0.62) | MMEACEHPGDCYP3A4TAAR1 | |
| SCHEMBL25358418 | 0.86 | TAAR1 (0.62) | MMEACEHPGDCYP3A4TAAR1 | |
| SCHEMBL11745127 | 0.83 | TAAR1 (0.67) | CYP3A4TAAR1SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL25201048 | 0.83 | TAAR1 (0.67) | CYP3A4TAAR1SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL26238861 | 0.83 | TAAR1 (0.67) | CYP3A4TAAR1SLC6A4CYP2D6SLC6A2 | |
| SCHEMBL7834954 | 0.83 | HPGD (0.77) | MMEACEITGB1ITGA4HPGD | |
| SCHEMBL8409073 | 0.83 | HPGD (0.77) | MMEACEITGB1ITGA4HPGD | |
| SCHEMBL9958965 | 0.83 | ACE (0.55) | MMEACEITGB1ITGA4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985567-A | Ligand for a Metal Complex Catalyst | KAZUO ACHIWA (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0336123-A2 | New chiral phosphinopyrrolidine compounds and their use for asymmetric synthesis of optically active compounds | FUJI YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1989-10-11 | — | — | EP | disclosed |