Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | ACE | P12821 | 3/20 | 0.62 |
| ▸ | MME | P08473 | 1/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.57 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | NSD2 | O96028 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7834954 | 1.00 | HPGD (0.77) | HPGDTSHRACEMMEITGB1 | |
| SCHEMBL31294604 | 0.87 | HPGD (1.00) | HPGDTSHRACEMMEITGB1 | |
| SCHEMBL11716412 | 0.85 | TAS1R3 (0.64) | HPGDTSHRALDH1A1ALOX12KDM4E | |
| SCHEMBL9838207 | 0.83 | MME (0.57) | HPGDACEMMEITGB1ITGA4 | |
| SCHEMBL7445244 | 0.83 | NPC1 (0.61) | HPGDTSHRACEMMEITGB1 | |
| SCHEMBL8412921 | 0.81 | HPGD (0.54) | HPGDTSHRACEMMENPC1 | |
| SCHEMBL4849622 | 0.81 | ALDH1A1 (0.59) | HPGDACEMMEITGB1ITGA4 | |
| SCHEMBL8412274 | 0.81 | HPGD (0.53) | HPGDTSHRACEITGB1ITGA4 | |
| SCHEMBL25358418 | 0.80 | TAAR1 (0.62) | HPGDACEMMEALDH1A1 | |
| SCHEMBL26008175 | 0.80 | TAAR1 (0.62) | HPGDACEMMEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5864041-A | REACTING N-ACYL-3,4-DIHYDROXYPHENYLALAMINE DERIVATIVE WITH A HALOGEN RADICAL GENERATOR, A CERIUM SALT IN PRESENCE OR ABSENCE OF COPPER SALT CATALYST, OR A PERSULFATE SALT WITH COPPER CATALYST; USEFUL FOR TREATING NERVOUS SYSTEM DISORDERS | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| US-5739387-A | CATALYTIC CYCLIZATION WITH A CERIUM SALT OR A PERSULFATE SALT, DECYCLIZATION, DEBLOCKING AND DEPROTECTING | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |