Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9701980 | 0.84 | CYP19A1 (0.56) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL8627499 | 0.83 | CYP19A1 (0.55) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL9701978 | 0.74 | PTGDR2 (0.43) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL9332121 | 0.73 | POLB (0.44) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL19458768 | 0.71 | KDM4E (0.41) | MEN1MAPTKMT2AADRA2AADRA2B | |
| SCHEMBL8444306 | 0.71 | KDM4E (0.49) | MEN1KMT2APOLB | |
| SCHEMBL27787420 | 0.69 | MAPT (0.46) | MEN1MAPTKMT2APOLBLMNA | |
| SCHEMBL29315511 | 0.68 | KDM4E (0.54) | MEN1KMT2APOLB | |
| SCHEMBL7794901 | 0.68 | CYP19A1 (0.46) | CYP19A1CYP11B1CYP11B2PTGDR2MEN1 | |
| SCHEMBL27696101 | 0.67 | HPGD (0.48) | MEN1MAPTKMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991003748-A1 | ELECTRO-OPTIC WAVEGUIDE DEVICE | HOECHST CELANESE CORPORATION (US) | 1991-03-21 | — | — | WO | disclosed |