Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750358 | 0.82 | DRD3 (0.66) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9837577 | 0.82 | LMNA (0.58) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9865549 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| Binfloxacin SCHEMBL1071552 | 0.78 | DRD3 (0.65) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9749538 | 0.78 | DRD3 (0.71) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| Binfloxacin SCHEMBL9369468 | 0.77 | DRD3 (0.64) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9749182 | 0.77 | DRD3 (0.69) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9670956 | 0.76 | DRD3 (0.63) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9749610 | 0.76 | DRD3 (0.63) | DRD3KDM4EALDH1A1HPGDHSD17B10 | |
| Binfloxacin SCHEMBL9366957 | 0.76 | KDM4E (0.68) | DRD3KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |