Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 4/20 | 0.43 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9866403 | 0.96 | KDM4E (0.58) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9838719 | 0.92 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9669484 | 0.87 | TOP2A (0.58) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9837294 | 0.85 | KDM4E (0.64) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9837357 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9867237 | 0.84 | TOP2A (0.55) | KDM4EALDH1A1HPGDHSD17B10KCNH2 | |
| SCHEMBL9837564 | 0.84 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9749429 | 0.84 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9838745 | 0.83 | KDM4E (0.56) | KDM4EALDH1A1HPGDHSD17B10PMP22 | |
| SCHEMBL9749610 | 0.82 | DRD3 (0.63) | KDM4EALDH1A1HPGDHSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159174-B1 | SUBSTITUTED NAPHTHYRIDINE-, QUINOLINE- AND BENZOXAZINE- CARBOXYLIC ACIDS AS ANTIBACTERIAL AGENTS AND PROCESSES FOR THEIR PRODUCTION | WARNER-LAMBERT COMPANY (US) | 1991-10-23 | — | — | EP | disclosed |
| US-4571396-A | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1986-02-18 | — | — | US | disclosed |
| EP-0159174-A2 | Substituted naphthyridine-, quinoline- and benzoxazine- carboxylic acids as antibacterial agents and processes for their production | WARNER-LAMBERT COMPANY (US) | 1985-10-23 | — | — | EP | disclosed |