Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | BIRC2 | Q13490 | 3/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 8/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10431470 | 0.87 | PRKCD (0.33) | CA2ZDHHC7BIRC2SMPD1 | |
| SCHEMBL9838257 | 0.86 | GRIK1 (0.41) | CA2FOLH1 | |
| SCHEMBL9326185 | 0.80 | PRKCD (0.39) | CA2SMPD1 | |
| SCHEMBL10431469 | 0.78 | PRKCD (0.32) | CA2SMPD1 | |
| SCHEMBL10461192 | 0.78 | GRIK1 (0.40) | CA2 | |
| SCHEMBL9766908 | 0.76 | ZDHHC7 (0.43) | CA2CA1ZDHHC7SMPD1ABCB1 | |
| SCHEMBL17678684 | 0.75 | BIRC2 (0.60) | FOLH1BIRC2MMP2MMP1MMP3 | |
| SCHEMBL10949180 | 0.75 | BIRC2 (0.60) | FOLH1BIRC2MMP2MMP1MMP3 | |
| SCHEMBL3155045 | 0.73 | BIRC2 (0.61) | CA2CA1FOLH1BIRC2MMP2 | |
| SCHEMBL9744772 | 0.73 | TACR3 (0.37) | ZDHHC7SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5059611-A | Treating psoriasis and modifying calcium homeostatis | ALLERGAN, INC. (US) | 1991-10-22 | — | — | US | disclosed |
| EP-0369812-A2 | Anti-inflammatory 5-hydroxy-2-furanones | ALLERGAN, INC (US) | 1990-05-23 | — | — | EP | disclosed |