SCHEMBL9744772

SCHEMBL9744772

CCCCCCCCCCCCC(NC(=O)OC)c1coc([Si](C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TACR3 P29371 2/20 0.37
ZDHHC7 Q9NXF8 1/20 0.35
EPHX1 P07099 1/20 0.34
FAAH O00519 4/20 0.33
SMPD1 P17405 1/20 0.33
HRH3 Q9Y5N1 3/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9325177 0.88 ALDH1A1 (0.39) TACR3SMPD1
SCHEMBL9328354 0.85 TACR3 (0.37) TACR3ZDHHC7
SCHEMBL9326801 0.83 EPHX1 (0.37) TACR3EPHX1FAAH
SCHEMBL7326578 0.79 ALDH1A1 (0.38) TACR3SMPD1
SCHEMBL9766908 0.78 ZDHHC7 (0.43) ZDHHC7FAAHSMPD1CYP3A4CYP2C9
SCHEMBL9326410 0.78 CA2 (0.32)
SCHEMBL9671711 0.77 EPHX1 (0.35) ZDHHC7EPHX1FAAHSMPD1
SCHEMBL7301168 0.76 CA2 (0.40) CYP3A4CYP2C9CYP2C19
SCHEMBL7303995 0.76 CA2 (0.40) CYP3A4CYP2C9CYP2C19
SCHEMBL9325034 0.75 GLS2 (0.35) FAAHSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5089485-A ANTI-INFLAMMATORY FURANONES ALLERGAN, INC. (US) 1992-02-18 US disclosed