Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839611 | 1.00 | RARB (0.63) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL10824195 | 1.00 | RARB (0.63) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL11180480 | 0.87 | RARB (0.58) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL10582913 | 0.82 | RAB9A (0.63) | MAPTRAB9ANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1513188 | 0.82 | KCNH2 (0.71) | RARBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9840084 | 0.82 | MAPT (0.79) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9220200 | 0.82 | MAPT (0.79) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9615976 | 0.82 | MAPT (0.79) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL9850160 | 0.82 | MAPT (0.79) | RARBMAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL7159512 | 0.82 | MAPT (0.79) | RARBMAPTRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030383-A | With low temperature dependence of threshold voltage | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-07-09 | — | — | US | disclosed |
| EP-0258349-B1 | ELECTRO-OPTICAL DISPLAY ELEMENT | MERCK PATENT GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0258349-A1 | ELECTRO-OPTICAL DISPLAY ELEMENT. | MERCK PATENT GMBH (DE) | 1988-03-09 | — | — | EP | disclosed |
| WO-1987005318-A1 | ELECTRO-OPTICAL DISPLAY ELEMENT | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1987-09-11 | — | — | WO | disclosed |