Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9838942 | 0.84 | MEN1 (0.49) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL9838931 | 0.84 | MEN1 (0.49) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL9838013 | 0.82 | MEN1 (0.41) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL10739830 | 0.80 | MEN1 (0.47) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL10682228 | 0.76 | MEN1 (0.39) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL9798904 | 0.76 | TSHR (0.51) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL10738072 | 0.75 | MEN1 (0.39) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL10733323 | 0.75 | RAB9A (0.42) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL10684028 | 0.74 | MEN1 (0.36) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL10678925 | 0.74 | MEN1 (0.36) | RAB9AMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0124992-B1 | HERBICIDAL CYCLOHEXANE-1,3-DIONE DERIVATIVES | ICI AUSTRALIA LIMITED (AU) | 1991-05-29 | — | — | EP | disclosed |
| US-4680400-A | Herbicidal cyclohexane-1,3-dione-5-isoquinoline derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-07-14 | — | — | US | disclosed |
| US-4640708-A | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1987-02-03 | — | — | US | disclosed |
| EP-0124992-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1984-11-14 | — | — | EP | disclosed |