Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9839992 | 0.78 | TSHR (0.59) | SMN1; SMN2TSHRTDP1CHRM2CHRM4 | |
| SCHEMBL9838594 | 0.76 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1TSHRTDP1CHRM2 | |
| SCHEMBL28768511 | 0.76 | TSHR (0.39) | ALDH1A1TSHRTDP1CHRM2CHRM4 | |
| SCHEMBL10617924 | 0.76 | — | — | |
| SCHEMBL2220653 | 0.76 | — | — | |
| SCHEMBL27696656 | 0.75 | TSHR (0.37) | TSHRTDP1KMT2ALMNA | |
| SCHEMBL10011167 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TSHRTDP1CA14 | |
| SCHEMBL10012355 | 0.74 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1TSHRTDP1CA14 | |
| SCHEMBL27621164 | 0.73 | TSHR (0.36) | SMN1; SMN2TSHRTDP1MAPTLMNA | |
| SCHEMBL5864497 | 0.72 | TSHR (0.50) | SMN1; SMN2ALDH1A1TSHRTDP1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051530-A | Ester derivatives and process for production thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1991-09-24 | — | — | US | claimed |
| US-5051530-A | Ester derivatives and process for production thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1991-09-24 | — | — | US | disclosed |