Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.41 |
| ▸ | APEX1 | P27695 | 3/20 | 0.41 |
| ▸ | APAF1 | O14727 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 5/20 | 0.39 |
| ▸ | PGR | P06401 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10794298 | 0.93 | NR1I2 (0.46) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL5823403 | 0.92 | TDP1 (0.50) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL10490080 | 0.91 | TDP1 (0.42) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL10490083 | 0.91 | TDP1 (0.42) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9840190 | 0.90 | MAPT (0.40) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9840192 | 0.90 | MAPT (0.40) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9667985 | 0.89 | TDP1 (0.42) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9667991 | 0.89 | TDP1 (0.42) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9667500 | 0.89 | TDP1 (0.42) | TDP1APEX1APAF1LMNAL3MBTL1 | |
| SCHEMBL9667504 | 0.89 | TDP1 (0.42) | TDP1APEX1APAF1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073551-A | Antibiotics | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1991-12-17 | — | — | US | disclosed |
| EP-0335390-A2 | Novel cephalosporin compounds | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1989-10-04 | — | — | EP | disclosed |
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | disclosed |