Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840170 | 0.93 | TDP1 (0.41) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL9483140 | 0.91 | NR1I2 (0.47) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL10943901 | 0.90 | MAPT (0.46) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL11288738 | 0.90 | MAPT (0.46) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL9662765 | 0.90 | MAPT (0.48) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL11288735 | 0.90 | MAPT (0.46) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL9662774 | 0.90 | MAPT (0.48) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL10943896 | 0.90 | MAPT (0.46) | NR1I2MAPTALDH1A1USP2CYP3A4 | |
| SCHEMBL6362892 | 0.89 | PTGS1 (0.55) | NR1I2MAPTALDH1A1CYP3A4HPGD | |
| SCHEMBL6362891 | 0.89 | PTGS1 (0.55) | NR1I2MAPTALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4708955-A | ANTIBACTERIALS | BRISTOL-MYERS COMPANY (US) | 1987-11-24 | — | — | US | disclosed |