SCHEMBL9840263

SCHEMBL9840263

CCOCn1c(Br)c(C#N)c(F)c1-c1ccc(Cl)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.34
KDM4E B2RXH2 7/20 0.34
HPGD P15428 6/20 0.34
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.33
GRIA2 P42262 1/20 0.33
GRIA4 P48058 1/20 0.33
HTT P42858 1/20 0.32
MEN1 O00255 2/20 0.32
RXFP1 Q9HBX9 3/20 0.31
NPSR1 Q6W5P4 2/20 0.31
MAPT P10636 1/20 0.31
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
MAPK14 Q16539 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL678557 0.79 KMT2A (0.41) ALDH1A1KDM4EHPGDKMT2ALMNA
Chlorfenapyr SCHEMBL40337 0.78 RXFP1 (0.35) ALDH1A1KDM4EHPGDKMT2ALMNA
SCHEMBL10590618 0.77 KDM4E (0.36) ALDH1A1KDM4EHPGDKMT2ALMNA
Chlorfenapyr SCHEMBL27488880 0.77 RXFP1 (0.35) ALDH1A1KDM4EHPGDKMT2ALMNA
Chlorfenapyr SCHEMBL28530561 0.77 RXFP1 (0.35) ALDH1A1KDM4EHPGDKMT2ALMNA
SCHEMBL27810755 0.76 GRIA2 (0.34) ALDH1A1KDM4EHPGDKMT2ALMNA
Chlorfenapyr SCHEMBL28508419 0.76 RXFP1 (0.36) ALDH1A1KDM4EHPGDKMT2ALMNA
SCHEMBL9567374 0.76 RXFP1 (0.34) ALDH1A1KDM4EHPGDKMT2ALMNA
SCHEMBL5812558 0.75 RXFP1 (0.36) ALDH1A1KDM4EHPGDKMT2ALMNA
SCHEMBL7782866 0.74 NPSR1 (0.35) ALDH1A1KDM4EHPGDKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5010098-A Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof AMERICAN CYANAMID COMPANY (US) 1991-04-23 US disclosed
US-4929634-A ARYLPYRROLE COMPOUNDS AMERICAN CYANAMID COMPANY (US) 1990-05-29 US disclosed