Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA7 | P43166 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455022 | 0.85 | KDM4E (0.47) | NR1H2HPGDTSHREPHX1LMNA | |
| SCHEMBL10455020 | 0.85 | KDM4E (0.47) | NR1H2HPGDTSHREPHX1LMNA | |
| SCHEMBL6663908 | 0.77 | CA12 (0.49) | HPGDTSHRCA1CA2CA12 | |
| SCHEMBL16752107 | 0.77 | ADORA2A (0.48) | EPHX1LMNAHSD17B10CYP2D6CYP2C9 | |
| SCHEMBL3724500 | 0.77 | NR1H2 (0.50) | NR1H2HPGDTSHRCA1CA2 | |
| SCHEMBL10338884 | 0.77 | NR1H2 (0.50) | NR1H2HPGDTSHRCA1CA2 | |
| SCHEMBL9808114 | 0.74 | HSP90AA1 (0.40) | NR1H2HPGDTSHREPHX1CA1 | |
| SCHEMBL10633915 | 0.71 | ESR1 (0.52) | NR1H2HPGDCA1CA2CA12 | |
| SCHEMBL1727364 | 0.71 | NR1H2 (0.44) | NR1H2HPGDCA1CA2CA12 | |
| SCHEMBL3234308 | 0.71 | ESR1 (0.52) | NR1H2HPGDCA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4981970-A | LEUCO DYES, RECORDING | RICOH COMPANY, LTD. (JP) | 1991-01-01 | — | — | US | disclosed |
| US-4940691-A | Coloring phthalide compounds and recording materials using the compounds as coloring component | RICOH COMPANY, LTD. (JP) | 1990-07-10 | — | — | US | disclosed |
| US-4880762-A | OPTICAL RECORDING MEDIA | RICOH COMPANY, LTD. (JP) | 1989-11-14 | — | — | US | disclosed |