Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 14/20 | 0.80 |
| ▸ | MAOA | P21397 | 3/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | CASP7 | P55210 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.49 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22041637 | 0.89 | GPR35 (0.78) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL9587791 | 0.83 | GPR35 (0.77) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL22654541 | 0.82 | GPR35 (1.00) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL28598264 | 0.81 | GPR35 (1.00) | GPR35HPGDALDH1A1LMNA | |
| SCHEMBL3080344 | 0.79 | GPR35 (1.00) | GPR35MAOAMAOBHPGDGRIN1 | |
| SCHEMBL22041605 | 0.77 | GPR35 (0.74) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL982630 | 0.77 | GPR35 (0.72) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL22041606 | 0.76 | GPR35 (0.71) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL6479840 | 0.76 | GPR35 (0.65) | GPR35MAOAMAOBHPGDUSP2 | |
| SCHEMBL9319388 | 0.76 | GPR35 (0.82) | GPR35HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5019570-A | Antibioics | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-05-28 | — | — | US | disclosed |