Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MGAM | O43451 | 1/20 | 0.54 |
| ▸ | SI | P14410 | 1/20 | 0.54 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840301 | 1.00 | GAA (0.54) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL9127380 | 0.84 | NPSR1 (0.53) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL7450064 | 0.81 | NPSR1 (0.54) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL9060790 | 0.79 | NPSR1 (0.52) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL30365953 | 0.78 | NPSR1 (0.57) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL3303689 | 0.78 | NPSR1 (0.57) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL10371321 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL28405928 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL9838216 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2NPSR1 | |
| SCHEMBL10371323 | 0.78 | GAA (0.56) | GAAMGAMSIMGAM2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011944-A | Substituted α-pyrones | CIBA-GEIGY CORPORATION (US) | 1991-04-30 | — | — | US | disclosed |
| EP-0344113-A2 | Substituted alpha-pyrones and naphthoquinones | CIBA-GEIGY AG (CH) | 1989-11-29 | — | — | EP | disclosed |