SCHEMBL9060790

SCHEMBL9060790

CCOC(=O)C=C(Cl)CCl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.52
HCAR2 Q8TDS4 1/20 0.43
ALDH1A1 P00352 5/20 0.39
SMN1; SMN2 Q16637 2/20 0.37
POLB P06746 2/20 0.37
HTT P42858 1/20 0.37
LMNA P02545 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPT P10636 2/20 0.36
ALOX15 P16050 1/20 0.36
MGAM O43451 1/20 0.36
GAA P10253 1/20 0.36
SI P14410 1/20 0.36
MGAM2 Q2M2H8 1/20 0.36
SOAT1 P35610 1/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34
CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7450064 0.84 NPSR1 (0.54) NPSR1HCAR2ALDH1A1POLBLMNA
SCHEMBL6275625 0.79
SCHEMBL9840295 0.79 GAA (0.54) NPSR1HCAR2ALDH1A1SMN1; SMN2LMNA
SCHEMBL9840301 0.79 GAA (0.54) NPSR1HCAR2ALDH1A1SMN1; SMN2LMNA
SCHEMBL9127380 0.79 NPSR1 (0.53) NPSR1HCAR2ALDH1A1SMN1; SMN2POLB
SCHEMBL8646347 0.78 NPSR1 (0.52) NPSR1HCAR2ALDH1A1SMN1; SMN2POLB
SCHEMBL20931276 0.78 NPSR1 (0.52) NPSR1HCAR2ALDH1A1SMN1; SMN2POLB
SCHEMBL9427312 0.78 NPSR1 (0.52) NPSR1HCAR2ALDH1A1SMN1; SMN2POLB
SCHEMBL11196356 0.78 NPSR1 (0.52) NPSR1HCAR2ALDH1A1SMN1; SMN2POLB
SCHEMBL10740449 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103305116-B A kind of photocuring anti-reflection film coating liquid and preparation method thereof and application WUHAN GREENCHEMICAL TECHNOLOGY CO., LTD. (CN) 2015-09-30 CN claimed
CN-103305116-A Photo-curing transparency-increased film coating solution as well as preparation method and application thereof WUHAN GREENCHEMICAL TECHNOLOGY CO LTD 2013-09-18 CN claimed
CN-105175413-A Solid Forms Of Nematocidal Sulfonamides DU PONT 2015-12-23 CN disclosed
CN-103305116-B A kind of photocuring anti-reflection film coating liquid and preparation method thereof and application WUHAN GREENCHEMICAL TECHNOLOGY CO., LTD. (CN) 2015-09-30 CN disclosed
CN-103857677-A Solid forms of nematicidal sulfonamides DU PONT 2014-06-11 CN disclosed
CN-103305116-A Photo-curing transparency-increased film coating solution as well as preparation method and application thereof WUHAN GREENCHEMICAL TECHNOLOGY CO LTD 2013-09-18 CN disclosed
CN-103304511-A Novel synthesis method of mirabegron SUZHOU UUGENE BIOPHARMA CO LTD 2013-09-18 CN disclosed
CN-103265457-A (R)-4-amino phenethyl-(2-hydroxy-2-phenylethyl)-tert-butyl carbamate synthesis method SUZHOU UUGENE BIOPHARMA CO LTD 2013-08-28 CN disclosed
CN-103232352-A (R)-4-(2-(2-hydroxyl-2-phenylethylamino)-ethyl) tert-butyl phenylcarbamate SUZHOU UUGENE BIOPHARMA CO LTD 2013-08-07 CN disclosed
CN-103232368-A Synthesizing method of (R)-4-nitrophenethyl-(2-hydroxy-2-phenylethyl)-tert-butyl carbamate SUZHOU UUGENE BIOPHARMA CO LTD 2013-08-07 CN disclosed
CN-103193730-A Synthesis method of mirabegron SUZHOU UUGENE BIOPHARMA CO LTD 2013-07-10 CN disclosed
CN-103193658-A Synthesis method of (R)-2-p-nitrobenzene ethylamine-1-phenethyl alcohol and salt thereof SUZHOU UUGENE BIOPHARMA CO LTD 2013-07-10 CN disclosed
CN-1117093-C Pyrazolo [1, 5-a ] pyrimidine derivatives, their use and compositions OTSUKA PHARMA CO LTD (JP) 2003-08-06 CN disclosed
CN-1299362-A Pyrazolo [1,5-a] pyrimidine derivatives OTSUKA PHARMA CO LTD (JP) 2001-06-13 CN disclosed
EP-0492628-B1 Reversible thermosensitive coloring composition, recording medium, recording method and image display apparatus using the recording medium RICOH KK (JP) 1996-07-03 EP disclosed
US-5432534-A Reversible thermosensitive coloring composition, recording medium, recording method, and image display apparatus using the recording medium RICOH COMPANY, LTD. (JP) 1995-07-11 US disclosed
US-5395433-A Containing electron donor coloring and electron acceptor compounds which react to induce color formation; printers for computers, facsimile apparatus RICOH COMPANY, LTD. (JP) 1995-03-07 US disclosed
EP-0623476-A1 Sheet material for heat transfer printing DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1994-11-09 EP disclosed
US-5296439-A Support with reversible thermosensitive coloring recording layer containing electron donor coloring compound, electron acceptor which reacts to induce color formation RICOH COMPANY, LTD. (JP) 1994-03-22 US disclosed
EP-0492628-A1 Reversible thermosensitive coloring composition, recording medium, recording method and image display apparatus using the recording medium Ricoh Company, Ltd (JP) 1992-07-01 EP disclosed