Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.50 |
| ▸ | ALB | P02768 | 2/20 | 0.50 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.50 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.50 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | POLG | P54098 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31206933 | 1.00 | KMT2A (0.64) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL31206716 | 0.98 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL31206848 | 0.98 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1POLB | |
| Calcium SCHEMBL31206833 | 0.98 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1POLB | |
| Potassium SCHEMBL31206720 | 0.98 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1POLB | |
| Magnesium SCHEMBL31206864 | 0.98 | KMT2A (0.63) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL29884375 | 0.79 | LMNA (0.51) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL27538427 | 0.79 | LMNA (0.50) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL131642 | 0.78 | LMNA (0.48) | KMT2AMEN1LMNAALDH1A1POLB | |
| SCHEMBL7087937 | 0.76 | LMNA (0.50) | KMT2AMEN1LMNAALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075446-A | Synthesis of tetrahydro-2-furylated pyrimidine derivatives | KOREA ADVANCED INSTITUTE OF SCIENCE & TECHNOLOGY (KR) | 1991-12-24 | — | — | US | disclosed |