Dixanthogen

Dixanthogen

SCHEMBL9840346

CCOC(=S)SSC(=S)OCC.O=CO

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
CYP2D6 P10635 1/20 0.47
CA12 O43570 2/20 0.39
CA1 P00915 2/20 0.39
CA2 P00918 2/20 0.39
CA9 Q16790 2/20 0.39
GLO1 Q04760 1/20 0.35
LMNA P02545 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HDAC3 O15379 2/20 0.34
HDAC4 P56524 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC7 Q8WUI4 2/20 0.34
HDAC2 Q92769 2/20 0.34
HDAC10 Q969S8 2/20 0.34
HDAC11 Q96DB2 2/20 0.34
HDAC8 Q9BY41 2/20 0.34
HDAC6 Q9UBN7 2/20 0.34
HDAC9 Q9UKV0 2/20 0.34
HDAC5 Q9UQL6 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dixanthogen SCHEMBL37053 0.87 ALDH1A1 (0.50) ALDH1A1CYP2D6CA12CA1CA2
Dixanthogen SCHEMBL1415905 0.85 ALDH1A1 (0.48) ALDH1A1CYP2D6CA12CA1CA2
Dixanthogen SCHEMBL11408546 0.85 ALDH1A1 (0.48) ALDH1A1CYP2D6CA12CA1CA2
Dixanthogen SCHEMBL7105038 0.82 ALDH1A1 (0.46) ALDH1A1CYP2D6CA12CA1CA2
SCHEMBL22702013 0.79 ALDH1A1 (0.50) ALDH1A1CYP2D6CA12CA1CA2
SCHEMBL6814504 0.77 ALDH1A1 (0.46) ALDH1A1CYP2D6CA12CA1CA2
SCHEMBL29383164 0.77 ALDH1A1 (0.46) ALDH1A1CYP2D6CA12CA1CA2
Dixanthogen SCHEMBL11787436 0.74 ALDH1A1 (0.41) ALDH1A1CYP2D6CA12CA1CA2
Formic Acid SCHEMBL28464215 0.74 ALDH1A1 (0.46) ALDH1A1CYP2D6CA12CA1CA2
SCHEMBL11830672 0.73 ALDH1A1 (0.43) ALDH1A1CYP2D6CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5074993-A Treating aqueous alkaline ore pulp with water soluble poly-amines, bubbling, preferential flotation INCO LIMITED (CA) 1991-12-24 US disclosed