Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003978 | 0.92 | ALDH1A1 (0.49) | PKMGRM2TSHRCYP3A4FFAR1 | |
| SCHEMBL11157955 | 0.88 | GRM2 (0.51) | PKMGRM2TSHRFFAR1HPGD | |
| SCHEMBL9881096 | 0.84 | ALDH1A1 (0.43) | PKMGRM2TSHRFFAR1HPGD | |
| SCHEMBL1324044 | 0.84 | TDP1 (0.61) | PKMGRM2TSHRCYP3A4MAPK1 | |
| SCHEMBL10466868 | 0.84 | GRM2 (0.54) | PKMGRM2TSHRCYP3A4CYP2C19 | |
| SCHEMBL15003900 | 0.84 | GRM2 (0.45) | GRM2TSHRFFAR1HPGDMAPT | |
| SCHEMBL3723345 | 0.84 | HPGD (0.66) | PKMGRM2TSHRCYP3A4CYP2C19 | |
| SCHEMBL15445683 | 0.83 | FFAR1 (0.43) | PKMGRM2FFAR1HPGDALDH1A1 | |
| SCHEMBL9999539 | 0.83 | FFAR1 (0.43) | PKMGRM2FFAR1HPGDALDH1A1 | |
| SCHEMBL15003899 | 0.80 | HPGD (0.50) | PKMGRM2TSHRCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991002515-A1 | ANTI-INFLAMMATORY SUBSTANCES FOR COSMETIC PREPARATION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1991-03-07 | — | — | WO | disclosed |