Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.44 |
| ▸ | MC5R | P33032 | 2/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 9/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.37 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | IL6 | P05231 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992498 | 0.94 | CHEK1 (0.42) | MC4RMC5RMC3RCHEK1NAMPT | |
| SCHEMBL7999494 | 0.85 | CHEK1 (0.38) | CHEK1NAMPTSCN8ACXCR4CHRM2 | |
| SCHEMBL7993913 | 0.81 | CHEK1 (0.40) | CHEK1NAMPTSCN8ACXCR4SLC40A1 | |
| SCHEMBL26469110 | 0.78 | CHEK1 (0.41) | CHEK1NAMPTSLC40A1EGLN1 | |
| SCHEMBL7992276 | 0.77 | CHEK1 (0.48) | MC4RMC5RMC3RCHEK1TLR7 | |
| SCHEMBL10483919 | 0.76 | MC4R (0.47) | MC4RMC5RMC3RCHEK1KAT2B | |
| SCHEMBL10483916 | 0.76 | MC4R (0.47) | MC4RMC5RMC3RKAT2BCXCR4 | |
| SCHEMBL7992477 | 0.76 | KDM4E (0.50) | MC4RMC5RMC3RKAT2BCXCR4 | |
| SCHEMBL10483999 | 0.76 | MC4R (0.47) | MC4RMC5RMC3RKAT2BSCN8A | |
| SCHEMBL9885618 | 0.76 | SCN8A (0.55) | MC4RMC5RMC3RKAT2BSCN8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0212600-B1 | NITROMETHYLENE DERIVATIVES | NIHON BAYER AGROCHEM K.K. (JP) | 1991-11-27 | — | — | EP | disclosed |
| US-4812454-A | Nitromethylene derivatives and their use as insecticides | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-03-14 | — | — | US | disclosed |
| US-4772620-A | MITICIDES, PARASITICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1988-09-20 | — | — | US | disclosed |
| EP-0212600-A2 | Nitromethylene derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1987-03-04 | — | — | EP | disclosed |