Cyclopropane

Cyclopropane

SCHEMBL98406

C1CC1.O=C(CS)OCCOC(=O)CS

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
DGKA P23743 1/20 0.34
TDP1 Q9NUW8 1/20 0.32
ADRA2A P08913 1/20 0.32
ADRA1A P35348 1/20 0.32
MAPT P10636 2/20 0.31
BLM P54132 1/20 0.31
ALDH1A1 P00352 2/20 0.30
APOBEC3A P31941 1/20 0.30
APOBEC3G Q9HC16 1/20 0.30
NAAA Q02083 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL8420400 1.00 TSHR (0.43) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL11357980 1.00 TSHR (0.43) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL59459 0.91 TSHR (0.50) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL11224122 0.88 TSHR (0.48) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL10898409 0.88 TSHR (0.48) TSHRHSD17B10DGKATDP1ADRA2A
Ethylene SCHEMBL812649 0.86 TSHR (0.46) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL98638 0.83 TSHR (0.43) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL13864201 0.83 TSHR (0.43) TSHRHSD17B10DGKATDP1ADRA2A
Ethylene Glycol SCHEMBL1468277 0.83 TSHR (0.43) TSHRHSD17B10DGKATDP1ADRA2A
SCHEMBL97649 0.83 TSHR (0.43) TSHRHSD17B10DGKATDP1ADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492293-B2 Multi-component systems for preparing foamed products ARKEMA FRANCE (FR) 2025-12-09 US disclosed
EP-3891210-B1 MULTI-COMPONENT SYSTEMS FOR PREPARING FOAMED PRODUCTS ARKEMA FRANCE (FR) 2023-08-23 EP disclosed
US-20220033606-A1 MULTI-COMPONENT SYSTEMS FOR PREPARING FOAMED PRODUCTS ARKEMA FRANCE (FR) 2022-02-03 US disclosed
EP-3891210-A1 MULTI-COMPONENT SYSTEMS FOR PREPARING FOAMED PRODUCTS ARKEMA FRANCE (FR) 2021-10-13 EP disclosed
US-11130891-B2 Photocurable sealing material BOSTIK SA (FR) 2021-09-28 US disclosed
US-20210054251-A1 Photocurable Sealing Material BOSTIK SA (FR) 2021-02-25 US disclosed
EP-3744807-A1 PHOTOCURABLE SEALING MATERIAL Bostik SA (FR) 2020-12-02 EP disclosed
WO-2020115560-A1 MULTI-COMPONENT SYSTEMS FOR PREPARING FOAMED PRODUCTS ARKEMA FRANCE (FR) 2020-06-11 WO disclosed
EP-2426162-B1 ENERGY-RAY-CURABLE ELASTOMER COMPOSITION, MATERIAL FOR GASKET, GASKET, AND HARD DISK DEVICE BRIDGESTONE CORP (JP) 2017-09-27 EP disclosed
US-9303123-B2 Energy-ray-curable elastomer composition, material for gasket, gasket, and hard disk device BRIDGESTONE CORPORATION (JP) 2016-04-05 US disclosed
EP-2471873-B1 ENERGY RAY-CURABLE GASKET BRIDGESTONE CORP (JP) 2015-09-30 EP disclosed
US-20150080509-A1 PHOTOCURABLE MATERIAL FOR SEALING, SEALING METHOD, SEALING MATERIAL, AND HOUSING USING SAID SEALING MATERIAL NITTA GELATIN KK (JP) 2015-03-19 US disclosed
US-8921446-B2 Photocurable material for sealing, sealing method, sealing material, and housing using said sealing material NITTA GELATIN INC. (JP) 2014-12-30 US disclosed
US-20130303651-A1 PHOTOCURABLE MATERIAL FOR SEALING, SEALING METHOD, SEALING MATERIAL, AND HOUSING USING SAID SEALING MATERIAL BOSTIK SA (FR) 2013-11-14 US disclosed
EP-2471873-A1 ENERGY RAY-CURABLE ELASTOMER COMPOSITION Bridgestone Corporation (JP) 2012-07-04 EP disclosed
US-20120157564-A1 ENERGY RAY-CURABLE ELASTOMER COMPOSITION BRIDGESTONE CORPORATION (JP) 2012-06-21 US disclosed
EP-2426162-A1 ENERGY-RAY-CURABLE ELASTOMER COMPOSITION, MATERIAL FOR GASKET, GASKET, AND HARD DISK DEVICE Bridgestone Corporation (JP) 2012-03-07 EP disclosed
US-20120041096-A1 ENERGY-RAY-CURABLE ELASTOMER COMPOSITION, MATERIAL FOR GASKET, GASKET, AND HARD DISK DEVICE BRIDGESTONE CORPORATION (JP) 2012-02-16 US disclosed