Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840844 | 0.88 | MAPT (0.48) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9230491 | 0.85 | MAPT (0.52) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9325800 | 0.77 | KDM4E (0.37) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9614654 | 0.76 | MAPT (0.40) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9745987 | 0.74 | MAPT (0.35) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9323992 | 0.73 | MAPT (0.52) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9840851 | 0.73 | MAPT (0.48) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10428734 | 0.72 | MAPT (0.48) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL10428597 | 0.72 | MAPT (0.48) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL9224085 | 0.72 | MAPT (0.50) | KDM4EMAPTTHRBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4986934-A | SPIROBENZOXAZINE PYRROLOPYRIDINE COMPOUNDS, EYEGLASSES | PPG INDUSTRIES, INC. (US) | 1991-01-22 | — | — | US | disclosed |