Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | THRB | P10828 | 5/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9840832 | 0.85 | KDM4E (0.40) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9325800 | 0.83 | KDM4E (0.37) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL5345117 | 0.82 | MAPT (0.79) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9323992 | 0.81 | MAPT (0.52) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9614654 | 0.80 | MAPT (0.40) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9224085 | 0.80 | MAPT (0.50) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9226446 | 0.79 | MAPT (0.58) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL9745987 | 0.78 | MAPT (0.35) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL10428638 | 0.77 | MAPT (0.51) | MAPTTHRBTDP1KDM4ESMN1; SMN2 | |
| SCHEMBL29565466 | 0.76 | MAPT (0.48) | MAPTTHRBTDP1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0324786-B1 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME | PPG INDUSTRIES INC (US) | 1995-08-02 | — | — | EP | claimed |
| EP-0324786-A1 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME. | PPG INDUSTRIES INC (US) | 1989-07-26 | — | — | EP | claimed |
| EP-0324786-A4 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME. | PPG INDUSTRIES INC (US) | 1989-06-26 | — | — | EP | claimed |
| WO-1988002371-A1 | PHOTOCHROMIC SPIRO(INDOLINE) BENZOXAZINES AND ARTICLES CONTAINING THE SAME | PPG INDUSTRIES, INC. (US) | 1988-04-07 | — | — | WO | claimed |