Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749273 | 0.98 | RARB (0.47) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9840691 | 0.97 | RARB (0.53) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL10747027 | 0.96 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9839372 | 0.96 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9839415 | 0.96 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9840367 | 0.96 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9840317 | 0.96 | RARB (0.55) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9839416 | 0.94 | MAPT (0.49) | RARBMAPTSMN1; SMN2RAB9ANPC1 | |
| SCHEMBL9357530 | 0.88 | RARB (0.59) | RARBMAPTSMN1; SMN2RAB9ANFKB1 | |
| SCHEMBL9238955 | 0.88 | RARB (0.62) | RARBMAPTSMN1; SMN2RAB9ANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0220297-B1 | NITROGEN-CONTAINING HETEROCYCLES | MERCK PATENT GmbH (DE) | 1991-12-11 | — | — | EP | disclosed |
| US-4834904-A | FERROELECTRIC LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1989-05-30 | — | — | US | disclosed |