Fluoride

Fluoride

SCHEMBL9841299

CCCCCOc1ccc(COc2ccc([S])cc2)cc1.CCCCCOc1ccc(COc2ccc([S])cc2)cc1.CCCCCOc1ccc(COc2ccc([S])cc2)cc1.CCCCCOc1ccc(COc2ccc([S])cc2)cc1.CCCCCOc1ccc(COc2ccc([S])cc2)cc1.F.F.F.F.F

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.54
LTA4H P09960 3/20 0.51
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
APP P05067 2/20 0.46
HRH3 Q9Y5N1 1/20 0.46
TP53 P04637 2/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.45
PLA2G4B P0C869 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL9841296 0.98 NR5A1 (0.57) NR5A1LTA4HNPC1RAB9ATP53
Fluoride SCHEMBL9841761 0.98 NR5A1 (0.57) NR5A1LTA4HNPC1RAB9ATP53
Fluoride SCHEMBL9841619 0.97 APP (0.49) NR5A1LTA4HAPPTSHR
Fluoride SCHEMBL9841316 0.90 APP (0.49) LTA4HAPPHRH3
Fluoride SCHEMBL9841357 0.89 HRH3 (0.58) LTA4HRAB9AHRH3TP53
SCHEMBL2091079 0.88 NR5A1 (0.62) NR5A1LTA4HNPC1RAB9ATP53
Fluoride SCHEMBL9841709 0.87 HRH3 (0.57) LTA4HHRH3TP53
Fluoride SCHEMBL9841505 0.87 HRH3 (0.57) LTA4HHRH3TP53
Fluoride SCHEMBL9841864 0.87 HRH3 (0.57) LTA4HHRH3TP53
Fluoride SCHEMBL9841933 0.87 NR5A1 (0.54) NR5A1LTA4HNPC1RAB9ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055223-A For use in liquid crystal display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed