Fluoride

Fluoride

SCHEMBL9841933

CCCCCCCOc1ccc(CCc2ccc([S])cc2)cc1.CCCCCCCOc1ccc(CCc2ccc([S])cc2)cc1.CCCCCCCOc1ccc(CCc2ccc([S])cc2)cc1.CCCCCCCOc1ccc(CCc2ccc([S])cc2)cc1.CCCCCCCOc1ccc(CCc2ccc([S])cc2)cc1.F.F.F.F.F

nearest known ligand 0.54

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR5A1 Q13285 1/20 0.54
MEN1 O00255 1/20 0.54
USP2 O75604 1/20 0.54
ALDH1A1 P00352 1/20 0.54
LMNA P02545 1/20 0.54
CYP3A4 P08684 1/20 0.54
MAPK1 P28482 1/20 0.54
CASP1 P29466 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
SLCO1B3 Q9NPD5 1/20 0.54
SLCO1B1 Q9Y6L6 1/20 0.54
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
S1PR4 O95977 2/20 0.49
S1PR1 P21453 2/20 0.49
S1PR3 Q99500 2/20 0.49
S1PR5 Q9H228 1/20 0.49
TP53 P04637 2/20 0.49
HPGD P15428 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL9841200 1.00 NR5A1 (0.54) NR5A1MEN1USP2ALDH1A1LMNA
Fluoride SCHEMBL9842024 1.00 NR5A1 (0.54) NR5A1MEN1USP2ALDH1A1LMNA
Fluoride SCHEMBL9841393 0.95 LMNA (0.50) MEN1USP2ALDH1A1LMNACYP3A4
SCHEMBL29962325 0.89 NR5A1 (0.66) NR5A1MEN1USP2ALDH1A1LMNA
SCHEMBL11226743 0.89 NR5A1 (0.66) NR5A1LMNANPC1RAB9ATP53
SCHEMBL3841866 0.89 NR5A1 (0.66) NR5A1LMNANPC1RAB9ATP53
SCHEMBL8356940 0.89 NR5A1 (0.66) NR5A1LMNANPC1RAB9ATP53
SCHEMBL2097863 0.89 NR5A1 (0.66) NR5A1LMNANPC1RAB9ATP53
SCHEMBL12587660 0.89 NR5A1 (0.66) NR5A1MEN1USP2ALDH1A1LMNA
Fluoride SCHEMBL9841761 0.89 NR5A1 (0.57) NR5A1MEN1USP2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5055223-A For use in liquid crystal display elements MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1991-10-08 US disclosed