Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841381 | 0.96 | HTT (0.40) | MAPTGAAATMCA2TP53 | |
| Fluoride SCHEMBL9841547 | 0.96 | HTT (0.40) | MAPTGAAATMCA2TP53 | |
| Fluoride SCHEMBL9841286 | 0.93 | ATM (0.40) | MAPTGAAATMCA2POLB | |
| SCHEMBL7507918 | 0.88 | MAPT (0.43) | MAPTGAAATMCA2TP53 | |
| SCHEMBL20152452 | 0.88 | MAPT (0.43) | MAPTGAAATMCA2TP53 | |
| SCHEMBL8455047 | 0.88 | MAPT (0.43) | MAPTGAAATMCA2TP53 | |
| Fluoride SCHEMBL9841305 | 0.88 | KMT2A (0.41) | MAPTGAAATMCA2POLB | |
| Fluoride SCHEMBL9841262 | 0.86 | GAA (0.40) | MAPTGAAATMCA2TP53 | |
| Fluoride SCHEMBL9841742 | 0.86 | KMT2A (0.46) | MAPTGAAATMPOLBKMT2A | |
| SCHEMBL7508867 | 0.85 | TDP1 (0.42) | MAPTGAAATMCA2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |