Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluoride SCHEMBL9841381 | 1.00 | HTT (0.40) | HTTKMT2AMEN1PKMATM | |
| Fluoride SCHEMBL9841445 | 0.96 | MAPT (0.40) | HTTKMT2AATMCA2MAPT | |
| Fluoride SCHEMBL9841286 | 0.91 | ATM (0.40) | HTTKMT2AMEN1ATMCA2 | |
| SCHEMBL8455675 | 0.88 | TDP1 (0.42) | HTTKMT2AMEN1PKMATM | |
| SCHEMBL20152463 | 0.88 | TDP1 (0.42) | HTTKMT2AMEN1PKMATM | |
| SCHEMBL7508867 | 0.88 | TDP1 (0.42) | HTTKMT2AMEN1PKMATM | |
| Fluoride SCHEMBL9841961 | 0.87 | HTT (0.40) | HTTKMT2AMEN1PKMATM | |
| Fluoride SCHEMBL9841320 | 0.87 | HTT (0.40) | HTTKMT2AMEN1PKMATM | |
| Fluoride SCHEMBL9841177 | 0.86 | HTT (0.44) | HTTKMT2AMEN1PKMATM | |
| Fluoride SCHEMBL9841714 | 0.86 | HTT (0.44) | HTTKMT2AMEN1PKMATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |