Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28553906 | 0.94 | MAOB (0.57) | MAOBMEN1KMT2ASMPD1SMN1; SMN2 | |
| SCHEMBL4910012 | 0.86 | MEN1 (0.62) | MAOBMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL9841958 | 0.85 | MAOB (0.69) | MAOBMEN1KMT2ASMPD1EGLN2 | |
| SCHEMBL2735788 | 0.84 | MAOB (0.76) | MAOBMEN1KMT2AEGLN2AR | |
| SCHEMBL14601810 | 0.84 | MEN1 (0.61) | MAOBMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL9842230 | 0.84 | MAOB (0.71) | MAOBMEN1KMT2ASMPD1EGLN2 | |
| SCHEMBL403151 | 0.82 | MAOB (1.00) | MAOBEGLN2ARSMN1; SMN2RAB9A | |
| SCHEMBL8618909 | 0.82 | MAOB (0.85) | MAOBSMPD1ARSMN1; SMN2TSHR | |
| SCHEMBL3271153 | 0.82 | CYP4F2 (0.61) | MAOBMEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL214243 | 0.80 | MAOB (0.65) | MAOBMEN1KMT2AEGLN2AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041516-A | Macromolecules | CORNELL RESEARCH FOUNDATION, INC. (US) | 1991-08-20 | — | — | US | disclosed |