Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841908 | 0.84 | MAPT (0.52) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10335493 | 0.83 | NPC1 (0.57) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9640160 | 0.83 | NPC1 (0.57) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9640628 | 0.83 | NPC1 (0.57) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9640089 | 0.83 | NPC1 (0.57) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9641053 | 0.83 | NPC1 (0.57) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL9905870 | 0.81 | LMNA (0.65) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL17515627 | 0.81 | LMNA (0.65) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL10484072 | 0.81 | MAPT (0.46) | LMNANPC1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL8774731 | 0.81 | MAPT (0.57) | LMNANPC1CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055223-A | For use in liquid crystal display elements | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-10-08 | — | — | US | disclosed |