SCHEMBL9842371

SCHEMBL9842371

CC[C@H]1CC[C@H](C(=O)Oc2ccc(-c3ccc(F)cc3)c(F)c2)CC1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.39
KMT2A Q03164 3/20 0.39
HTT P42858 2/20 0.39
KDM4E B2RXH2 1/20 0.39
HPGD P15428 1/20 0.39
TDP1 Q9NUW8 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
APP P05067 3/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
F2 P00734 1/20 0.37
F10 P00742 1/20 0.37
CYP2C19 P33261 2/20 0.37
FFAR4 Q5NUL3 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
ATM Q13315 1/20 0.37
DPP4 P27487 1/20 0.37
ELANE P08246 1/20 0.36
ALDH1A1 P00352 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9842698 0.89 TP53 (0.40) CA2KMT2AHTTKDM4EHPGD
SCHEMBL9842442 0.88 FFAR4 (0.35) CA2KMT2AHTTKDM4EHPGD
SCHEMBL9842603 0.88 RARB (0.39) CA2ATM
SCHEMBL9842435 0.87 APP (0.40) KMT2AHTTKDM4EHPGDTDP1
SCHEMBL9842608 0.87 RARB (0.40)
SCHEMBL9842792 0.87 RARB (0.40)
SCHEMBL9842479 0.87 RARB (0.40)
SCHEMBL9842569 0.87 RARB (0.40)
SCHEMBL9842649 0.87 RARB (0.40)
SCHEMBL11108679 0.86 KMT2A (0.49) CA2KMT2AHTTHPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed