Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.58 |
| ▸ | RARA | P10276 | 2/20 | 0.58 |
| ▸ | FAAH | O00519 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | RARG | P13631 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842396 | 0.93 | RARB (0.62) | RARBRARAFAAHCYP1A2CYP2C19 | |
| SCHEMBL9842575 | 0.92 | RARB (0.61) | RARBRARAFAAHCYP1A2CYP2C19 | |
| SCHEMBL9842460 | 0.92 | RARB (0.61) | RARBRARAFAAHCYP1A2CYP2C19 | |
| SCHEMBL9842671 | 0.86 | RARB (0.49) | RARBRARAFAAHCYP1A2CYP2C19 | |
| SCHEMBL9843123 | 0.85 | MAPT (0.54) | RARBRARAFAAHCYP1A2CYP2C19 | |
| SCHEMBL9842616 | 0.83 | RARB (0.60) | RARBRARAFAAHCYP1A2CYP2C19 | |
| SCHEMBL11101882 | 0.83 | MAPT (0.59) | RARBFAAHCYP1A2CYP2C19LMNA | |
| SCHEMBL11104232 | 0.83 | MAPT (0.59) | RARBFAAHCYP1A2CYP2C19LMNA | |
| SCHEMBL9842601 | 0.82 | RARB (0.66) | RARBRARAFAAHKMT2AMAPT | |
| SCHEMBL9842696 | 0.81 | RARB (0.68) | RARBRARAFAAHKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |