Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.62 |
| ▸ | RARA | P10276 | 2/20 | 0.62 |
| ▸ | FAAH | O00519 | 9/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.48 |
| ▸ | RELA | Q04206 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RARG | P13631 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842460 | 0.99 | RARB (0.61) | RARBRARAFAAHNPC1LMNA | |
| SCHEMBL9842575 | 0.99 | RARB (0.61) | RARBRARAFAAHNPC1LMNA | |
| SCHEMBL9842529 | 0.93 | RARB (0.58) | RARBRARAFAAHLMNACYP1A2 | |
| SCHEMBL9842601 | 0.87 | RARB (0.66) | RARBRARAFAAHNPC1SMN1; SMN2 | |
| SCHEMBL9842696 | 0.86 | RARB (0.68) | RARBRARAFAAHNPC1SMN1; SMN2 | |
| SCHEMBL9842545 | 0.86 | RARB (0.68) | RARBRARAFAAHNPC1SMN1; SMN2 | |
| SCHEMBL9842444 | 0.86 | RARB (0.68) | RARBRARAFAAHNPC1SMN1; SMN2 | |
| SCHEMBL9842616 | 0.86 | RARB (0.60) | RARBRARAFAAHNPC1CYP1A2 | |
| SCHEMBL9737006 | 0.85 | RARB (0.55) | RARBRARAFAAHNPC1LMNA | |
| SCHEMBL11106241 | 0.84 | LMNA (0.65) | RARBFAAHNPC1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |