Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.68 |
| ▸ | RARA | P10276 | 3/20 | 0.68 |
| ▸ | RARG | P13631 | 1/20 | 0.68 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842444 | 1.00 | RARB (0.68) | RARBRARARARGTHRBTHRA | |
| SCHEMBL9842696 | 1.00 | RARB (0.68) | RARBRARARARGTHRBTHRA | |
| SCHEMBL9842601 | 0.99 | RARB (0.66) | RARBRARARARGTHRBTHRA | |
| SCHEMBL9842616 | 0.95 | RARB (0.60) | RARBRARARARGTHRBTHRA | |
| SCHEMBL9843123 | 0.91 | MAPT (0.54) | RARBRARARARGTHRBMAPT | |
| SCHEMBL9842460 | 0.87 | RARB (0.61) | RARBRARARARGMAPTSMN1; SMN2 | |
| SCHEMBL9842575 | 0.87 | RARB (0.61) | RARBRARARARGMAPTSMN1; SMN2 | |
| SCHEMBL9842671 | 0.87 | RARB (0.49) | RARBRARARARGTHRBMAPT | |
| SCHEMBL9842396 | 0.86 | RARB (0.62) | RARBRARARARGMAPTSMN1; SMN2 | |
| SCHEMBL11102964 | 0.84 | MAPT (0.58) | RARBRARARARGTHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. | MERCK PATENT GMBH (DE) | 1991-02-27 | — | — | EP | disclosed |
| WO-1990009420-A1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-08-23 | — | — | WO | disclosed |