Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.65 |
| ▸ | PDE4A | P27815 | 4/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.65 |
| ▸ | BRD4 | O60885 | 3/20 | 0.58 |
| ▸ | BRD2 | P25440 | 2/20 | 0.58 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.58 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842911 | 0.96 | MEN1 (0.62) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL9842882 | 0.95 | MEN1 (0.60) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL7464187 | 0.92 | PDE4A (0.65) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL9842568 | 0.87 | PDE4A (0.59) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL9842711 | 0.86 | MEN1 (0.49) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL9842637 | 0.85 | MAPK1 (0.52) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL9842775 | 0.83 | SMN1; SMN2 (0.47) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL4566277 | 0.81 | MEN1 (0.77) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL7457891 | 0.80 | MEN1 (1.00) | ALDH1A1MEN1KMT2AADORA2APDE4A | |
| SCHEMBL9615238 | 0.80 | SMN1; SMN2 (0.44) | ALDH1A1MEN1KMT2AADORA2APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0430025-A2 | Xanthine compound, method for preparing thereof, and a pharmaceutical composition comprising the same | HOKURIKU PHARMACEUTICAL CO., LTD. (JP) | 1991-06-05 | — | — | EP | disclosed |