Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27972133 | 0.94 | — | — | |
| Acetone SCHEMBL28356829 | 0.85 | — | — | |
| Bicarbonate SCHEMBL48074 | 0.82 | — | — | |
| Methacrylic Acid SCHEMBL11405266 | 0.81 | ALDH1A1 (0.36) | FFAR3LCKFYNALDH1A1TSHR | |
| Hydrogen Peroxide SCHEMBL27900920 | 0.78 | — | — | |
| Acetic Acid SCHEMBL4557325 | 0.77 | — | — | |
| Acrylic Acid SCHEMBL11408787 | 0.77 | — | — | |
| Carbamic Acid SCHEMBL28133607 | 0.77 | — | — | |
| SCHEMBL11404668 | 0.76 | — | — | |
| Methyl Alcohol SCHEMBL3741971 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032319-A | Tin chloride, tin fluoroborate | TH. GOLDSCHMIDT AG (DE) | 1991-07-16 | — | — | US | disclosed |
| US-4965137-A | NONTOXIC | TH. GOLDSCHMIDT AG (DE) | 1990-10-23 | — | — | US | disclosed |
| US-4963437-A | Liquid preparation for the production of electrically conductive and infrared-reflecting fluorine-doped tin oxide layers on glass or glass-ceramic surfaces, as well as a method for the production of such layer | TH. GOLDSCHMIDT AG (DE) | 1990-10-16 | — | — | US | disclosed |