Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 11/20 | 0.58 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 2/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FABP3 | P05413 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8965139 | 0.77 | PTGDR2 (0.61) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8965332 | 0.76 | PTGDR2 (0.69) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8965345 | 0.76 | PTGDR2 (0.69) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8964950 | 0.74 | PTGDR2 (0.68) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL3164718 | 0.73 | PTGDR2 (1.00) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8804127 | 0.73 | PTGDR2 (0.67) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL3168673 | 0.73 | PTGDR2 (0.94) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8965375 | 0.72 | PTGDR2 (0.63) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8965280 | 0.72 | PTGDR2 (0.55) | PTGDR2PTGDRPTGIRPPARAPPARG | |
| SCHEMBL8965035 | 0.71 | PTGDR2 (0.55) | PTGDR2PTGDRPTGIRPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | claimed |
| US-4956376-A | ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-09-11 | — | — | US | claimed |
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4956376-A | ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1990-09-11 | — | — | US | disclosed |