SCHEMBL9842899

SCHEMBL9842899

Nc1ncccc1C1CCNC1

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 6/20 0.46
SLC6A2 P23975 6/20 0.46
SLC6A4 P31645 6/20 0.46
SLC6A3 Q01959 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29748769 0.90 IKBKB (0.46)
SCHEMBL1429509 0.90 HTR1A (0.55) HTR1ASLC6A2SLC6A4SLC6A3
Trifluoroacetic Acid SCHEMBL30176834 0.87 SSTR4 (0.42) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL29889329 0.80 HTR1A (0.49) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL29229137 0.80 HTR1A (0.46) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL29889413 0.80 HTR1A (0.49) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL30469945 0.80 PDK2 (0.46) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL934667 0.80 PDK2 (0.46) HTR1ASLC6A2SLC6A4SLC6A3
Potassium SCHEMBL29930626 0.78 PDK2 (0.45) HTR1ASLC6A2SLC6A4SLC6A3
SCHEMBL29013292 0.78 SLC6A4 (0.44) HTR1ASLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101360420-B Method of promoting enlargement growth of agricultural or horticultural crop KUMIAI CHEMICAL INDUSTRY CO 2013-05-08 CN disclosed
CN-101360420-A Method of promoting enlargement growth of agricultural or horticultural crop NAT UNIV CORP TOTTORI UNIV (JP) 2009-02-04 CN disclosed
EP-0420803-A2 Benzo-1,2,3-thiadiazole derivatives and their use for protecting plants against diseases CIBA-GEIGY AG (CH) 1991-04-03 EP disclosed
EP-0404721-A2 Microbicides CIBA-GEIGY AG (CH) 1990-12-27 EP disclosed
EP-0384890-A2 Agent to protect plants against diseases CIBA-GEIGY AG (CH) 1990-08-29 EP disclosed
EP-0384889-A2 Agent to protect plants against diseases CIBA-GEIGY AG (CH) 1990-08-29 EP disclosed
US-4897391-A Tricyclic anti-allergy, antiinflammatory and anti-hyperproliferative compounds SCHERING CORPORATION (US) 1990-01-30 US disclosed
EP-0334812-A2 Agents for the protection of plants against diseases CIBA-GEIGY AG (CH) 1989-09-27 EP disclosed
EP-0310558-A2 Microbicidal agent CIBA-GEIGY AG (CH) 1989-04-05 EP disclosed
EP-0236939-A1 Derivatives of 5-acyloxy-13-beta-alkyl milbemicyne against parasites in animals and plants CIBA-GEIGY AG (CH) 1987-09-16 EP disclosed