Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.73 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.71 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.71 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.71 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.71 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.71 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.71 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.71 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.71 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.71 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.71 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081226 | 0.93 | POLB (0.73) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13716202 | 0.93 | POLB (0.73) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8817395 | 0.89 | HDAC3 (0.76) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9312715 | 0.89 | POLB (0.84) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27663784 | 0.88 | HPGD (0.67) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2619349 | 0.88 | POLB (0.76) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4084296 | 0.87 | POLB (0.66) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL25269210 | 0.87 | ENPP2 (0.69) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27909135 | 0.87 | ENPP2 (0.69) | POLBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8867035 | 0.86 | HDAC3 (0.71) | POLBHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013148319-A1 | BACTERIAL IMAGING AGENTS AND METHODS OF USING SAME | VISEN MEDICAL, INC. (US) | 2013-10-03 | — | — | WO | disclosed |
| EP-0440503-A1 | 4-Isoxazolecarboxamide derivatives | SYNTEX (U.S.A.) INC. (US) | 1991-08-07 | — | — | EP | disclosed |