Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 7/20 | 0.34 |
| ▸ | MAP2K2 | P36507 | 2/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | TYMP | P19971 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL619959 | 0.93 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9761063 | 0.92 | LMNA (0.46) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8063055 | 0.90 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL32668972 | 0.90 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL11131957 | 0.90 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9513442 | 0.90 | LMNA (0.55) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL28469692 | 0.88 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL9191548 | 0.88 | LMNA (0.54) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL621824 | 0.86 | LMNA (0.52) | LMNACYP2C19HIF1AEGFRSRC | |
| Cadaverine Tartrate SCHEMBL9760947 | 0.85 | LMNA (0.47) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5004835-A | Substituted dicarboxylic acid-bis(3,5-dicarbamoyl-2,4,6-triiodoanilides), process for their production as well as X-ray contrast media containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-04-02 | — | — | US | disclosed |