Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791356 | 1.00 | PPM1B (0.50) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL25467328 | 1.00 | PPM1B (0.50) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL9537641 | 1.00 | PPM1B (0.50) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL3983188 | 0.98 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL3983080 | 0.98 | ALDH1A1 (0.49) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL3985705 | 0.96 | PPM1B (0.50) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL26077288 | 0.96 | PPM1B (0.50) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL15712143 | 0.91 | PPM1B (0.53) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL360031 | 0.83 | PPM1B (0.47) | PPM1BPTPN1PPP1CCNPC1RAB9A | |
| SCHEMBL19543310 | 0.82 | PPM1B (0.46) | PPM1BPTPN1PPP1CCALDH1A1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0421752-A2 | Substituted acrylamido-penicillanic acid derivatives | Beecham Group p.l.c. (GB) | 1991-04-10 | — | — | EP | disclosed |