SCHEMBL9843638

SCHEMBL9843638

C=CCCCCCCCCC[SiH2]O[SiH3]

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
ABCC4 O15439 1/20 0.35
MAPT P10636 1/20 0.35
ALDH1A1 P00352 3/20 0.35
LPAR3 Q9UBY5 2/20 0.35
LMNA P02545 1/20 0.35
LPAR2 Q9HBW0 1/20 0.35
TRPA1 O75762 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3133964 1.00 TSHR (0.41) TSHRABCC4MAPTALDH1A1LPAR3
SCHEMBL10776557 1.00 TSHR (0.41) TSHRABCC4MAPTALDH1A1LPAR3
SCHEMBL4160829 0.98
SCHEMBL16382560 0.94 TSHR (0.37) TSHRABCC4MAPTALDH1A1LPAR3
SCHEMBL10075642 0.81 TSHR (0.44) TSHRABCC4MAPTALDH1A1LPAR3
SCHEMBL977477 0.80
SCHEMBL8680820 0.77 TSHR (0.46) TSHRABCC4MAPTALDH1A1LPAR3
SCHEMBL17732447 0.77 TSHR (0.46) TSHRABCC4MAPTALDH1A1LPAR3
SCHEMBL15524323 0.75 MEN1 (0.33)
SCHEMBL27688035 0.72 TSHR (0.41) TSHRABCC4MAPTALDH1A1LPAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0409272-A1 Reaction products as adhesion additives for UV curable compositions and compositions containing same DOW CORNING CORPORATION (US) 1991-01-23 EP disclosed
EP-0356075-A2 UV curable siloxane composition containing an adhesion promoter DOW CORNING CORPORATION (US) 1990-02-28 EP disclosed