Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382560 | 0.89 | TSHR (0.37) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL10776557 | 0.81 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL9843638 | 0.81 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL17732447 | 0.81 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL8680820 | 0.81 | TSHR (0.46) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL3133964 | 0.81 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL4160829 | 0.78 | — | — | |
| SCHEMBL27723484 | 0.76 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL27688035 | 0.76 | TSHR (0.41) | TSHRMAPTABCC4ALDH1A1LPAR3 | |
| SCHEMBL12990141 | 0.75 | TSHR (0.44) | TSHRMAPTABCC4ALDH1A1LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170065514-A1 | CROSS-LINKED COMPOSITION AND COSMETIC COMPOSITION COMPRISING THE SAME | DOW SILICONES CORPORATION | 2017-03-09 | — | — | US | disclosed |
| US-8920783-B2 | Silicone-organic elastomer gels | DOW CORNING CORPORATION (US) | 2014-12-30 | — | — | US | disclosed |
| US-8541011-B2 | Silicone organic elastomer gels from organopolysiloxane resins | DOW CORNING CORPORATION (US) | 2013-09-24 | — | — | US | disclosed |
| US-20120258057-A1 | SILICONE ORGANIC ELASTOMER GELS FROM ORGANOPOLYSILOXANE RESINS | DOW SILICONES CORPORATION | 2012-10-11 | — | — | US | disclosed |
| US-8273840-B2 | Silicone polyether elastomer gels | DOW CORNING CORPORATION (US) | 2012-09-25 | — | — | US | disclosed |
| US-8236890-B2 | Emulsions of silicone elastomer and silicone organic elastomer gels | DOW CORNING CORPORATION (US) | 2012-08-07 | — | — | US | disclosed |
| US-8222363-B2 | Silicone organic elastomer gels from organopolysiloxane resins | DOW CORNING CORPORATION (US) | 2012-07-17 | — | — | US | disclosed |
| US-8110630-B2 | Silicone elastomer gels | DOW CORNING CORPORATION (US) | 2012-02-07 | — | — | US | disclosed |
| US-20100303743-A1 | Personal Care Compositions Containing Hydrophobic Silicone-Organic Gel Blends | DOW CORNING CORPORATION | 2010-12-02 | — | — | US | disclosed |
| US-20100247460-A1 | Silicone Organic Elastomer Gels From Organopolysiloxane Resins | DOW SILICONES CORPORATION | 2010-09-30 | — | — | US | disclosed |
| US-20100209367-A1 | Emulsions Of Silicone Elastomer And Silicone Organic Elastomer Gels | DOW CORNING CORPORATION | 2010-08-19 | — | — | US | disclosed |
| US-20100183525-A1 | SILICONE-ORGANIC ELASTOMER GELS | DOW CORNING CORPORATION | 2010-07-22 | — | — | US | disclosed |
| US-20100172856-A1 | SILICONE COPOLYMERS AND ELASTOMERS DERIVED FROM NATURAL OILS | DOW CORNING CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-20100172849-A1 | SILICONE ELASTOMER GELS | DOW SILICONES CORPORATION | 2010-07-08 | — | — | US | disclosed |
| US-20100158824-A1 | SILICONE POLYETHER ELASTOMER GELS | DOW SILICONES CORPORATION | 2010-06-24 | — | — | US | disclosed |
| US-20090317343-A1 | Personal Care Compositions Containing Silicone Elastomer Gels | DOW CORNING CORPORATION | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100172849-A1 | SILICONE ELASTOMER GELS | CCNH, DOHH, INTS9 | TSHR 3549/4885MAPT 3799/4885ABCC4 4170/4885 |
| US-20120258057-A1 | SILICONE ORGANIC ELASTOMER GELS FROM ORGANOPOLYSILOXANE RESINS | PIGS, IDUA, SERPINH1 | TSHR 3556/4885MAPT 3676/4885ABCC4 662/4885 |
| US-20170065514-A1 | CROSS-LINKED COMPOSITION AND COSMETIC COMPOSITION COMPRISING THE SAME | H1-0, H1-2, H1-3 | TSHR 2423/4885MAPT 4706/4885ABCC4 2509/4885 |
| US-20100209367-A1 | Emulsions Of Silicone Elastomer And Silicone Organic Elastomer Gels | CCNH, SUPT16H, ESD | TSHR 4250/4885MAPT 3622/4885ABCC4 3882/4885 |
| US-20100158824-A1 | SILICONE POLYETHER ELASTOMER GELS | DOHH, SUGT1, ESD | TSHR 3328/4885MAPT 3645/4885ABCC4 3809/4885 |
| US-20100303743-A1 | Personal Care Compositions Containing Hydrophobic Silicone-Organic Gel Blends | PLOD3, PLG, CUTA | TSHR 2848/4885MAPT 739/4885ABCC4 2565/4885 |
| US-20090317343-A1 | Personal Care Compositions Containing Silicone Elastomer Gels | MMS19, CUTA, ESD | TSHR 3320/4885MAPT 3052/4885ABCC4 4579/4885 |
| US-20100172856-A1 | SILICONE COPOLYMERS AND ELASTOMERS DERIVED FROM NATURAL OILS | SCLY, MMS19, ITCH | TSHR 3837/4885MAPT 3202/4885ABCC4 4449/4885 |
| US-20100247460-A1 | Silicone Organic Elastomer Gels From Organopolysiloxane Resins | PIGS, IDUA, SERPINH1 | TSHR 3556/4885MAPT 3676/4885ABCC4 662/4885 |
| US-20100183525-A1 | SILICONE-ORGANIC ELASTOMER GELS | DOHH, ESD, OGDH | TSHR 3293/4885MAPT 3506/4885ABCC4 3692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.