Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329111 | 0.82 | IDO1 (0.59) | IDO1DAONR3C2DPP4DPP8 | |
| SCHEMBL2879865 | 0.82 | IDO1 (0.44) | IDO1DAONPSR1NR3C2DPP4 | |
| SCHEMBL18240882 | 0.82 | IDO1 (0.44) | IDO1DAONPSR1NR3C2DPP4 | |
| SCHEMBL3517919 | 0.81 | IDO1 (0.52) | IDO1CA1CA2CA5ACA9 | |
| SCHEMBL31405344 | 0.81 | IDO1 (0.52) | IDO1CA1CA2CA5ACA9 | |
| SCHEMBL16268345 | 0.79 | SCN8A (0.48) | IDO1CA1CA2CA9NPSR1 | |
| SCHEMBL10623268 | 0.78 | CA1 (0.53) | IDO1DAOCA1CA2CA9 | |
| SCHEMBL28521875 | 0.76 | HDAC1 (0.49) | IDO1DAONPSR1NR3C2ALDH1A1 | |
| SCHEMBL9844112 | 0.76 | DAO (0.40) | IDO1DAONPSR1DPP4DPP8 | |
| SCHEMBL4881315 | 0.76 | TAAR1 (0.57) | IDO1DAOCA1CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |