Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18240882 | 0.76 | IDO1 (0.44) | DAOIDO1NPSR1ALDH1A1KDM4E | |
| SCHEMBL9843663 | 0.76 | IDO1 (0.49) | DAOIDO1NPSR1ALDH1A1KDM4E | |
| SCHEMBL2879865 | 0.76 | IDO1 (0.44) | DAOIDO1NPSR1ALDH1A1KDM4E | |
| SCHEMBL9843991 | 0.73 | ALDH1A1 (0.47) | ALDH1A1KMT2AHPGD | |
| SCHEMBL29030187 | 0.73 | FOLH1 (0.50) | ALDH1A1GAA | |
| SCHEMBL17329111 | 0.72 | IDO1 (0.59) | DAOIDO1ALDH1A1KDM4ETDP1 | |
| SCHEMBL5540181 | 0.72 | IDO1 (0.47) | DAOIDO1NPSR1ALDH1A1KDM4E | |
| SCHEMBL1950928 | 0.70 | IDO1 (0.46) | DAOIDO1NPSR1ALDH1A1KDM4E | |
| SCHEMBL28521875 | 0.70 | HDAC1 (0.49) | DAOIDO1NPSR1ALDH1A1KDM4E | |
| SCHEMBL31259918 | 0.69 | MEN1 (0.49) | ALDH1A1TDP1KMT2ACYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0447645-A1 | Aralkylesulfonyl ureas | BAYER AG (DE) | 1991-09-25 | — | — | EP | disclosed |