SCHEMBL9843677

SCHEMBL9843677

COC1C[C@H](O)[C@@H](COC(c2ccccc2)(c2ccccc2)c2ccccc2)O1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TYMP P19971 15/20 0.46
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
KIF11 P52732 1/20 0.34
CES1 P23141 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9843683 1.00 TYMP (0.46) TYMPMEN1KMT2AKIF11CES1
SCHEMBL9208332 0.93 TYMP (0.44) TYMPMEN1KMT2AKIF11
SCHEMBL10423328 0.93 TYMP (0.44) TYMPMEN1KMT2AKIF11
SCHEMBL9212681 0.93 TYMP (0.44) TYMPMEN1KMT2AKIF11
SCHEMBL9307929 0.92 TYMP (0.41) TYMPMEN1KMT2AKIF11
SCHEMBL9307935 0.92 TYMP (0.41) TYMPMEN1KMT2AKIF11
SCHEMBL10773292 0.92 TYMP (0.41) TYMPMEN1KMT2AKIF11
SCHEMBL10423647 0.85 MEN1 (0.38) TYMPMEN1KMT2AKIF11
SCHEMBL10423655 0.85 MEN1 (0.38) TYMPMEN1KMT2AKIF11
SCHEMBL10808189 0.83 TYMP (0.49) TYMPMEN1KMT2AKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450585-A2 Process for the manufacture of 2-deoxy-D-threo-pentofuranosides, intermediates for their manufacture and their use CHEMPROSA, CHEMISCHE PRODUKTE SAISCHEK GmbH (AT) 1991-10-09 EP claimed
EP-0450585-A2 Process for the manufacture of 2-deoxy-D-threo-pentofuranosides, intermediates for their manufacture and their use CHEMPROSA, CHEMISCHE PRODUKTE SAISCHEK GmbH (AT) 1991-10-09 EP disclosed
US-4898936-A ANTITUMOR AGENTS PCR, INC. (US) 1990-02-06 US disclosed
EP-0195805-A4 PROCESS FOR MAKING A 2-DEOXYURIDINE. SCM CORP (US) 1987-07-09 EP disclosed
US-4675390-A HYPOTENSIVE, ANTITUMOR, ANTICOAGULANT ELI LILLY AND COMPANY (US) 1987-06-23 US disclosed
EP-0195805-A1 PROCESS FOR MAKING A 2-DEOXYURIDINE PCR, Inc. (US) 1986-10-01 EP disclosed
WO-1986001801-A1 PROCESS FOR MAKING A 2-DEOXYURIDINE SCM CORPORATION (US) 1986-03-27 WO disclosed