Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 15/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9307929 | 1.00 | TYMP (0.41) | TYMPADORA1MEN1KMT2AKIF11 | |
| SCHEMBL10773292 | 1.00 | TYMP (0.41) | TYMPADORA1MEN1KMT2AKIF11 | |
| SCHEMBL9843677 | 0.92 | TYMP (0.46) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL9843683 | 0.92 | TYMP (0.46) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL9212681 | 0.85 | TYMP (0.44) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL9208332 | 0.85 | TYMP (0.44) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10423328 | 0.85 | TYMP (0.44) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10423647 | 0.83 | MEN1 (0.38) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10423655 | 0.83 | MEN1 (0.38) | TYMPMEN1KMT2AKIF11 | |
| SCHEMBL10758604 | 0.83 | PDE4D (0.38) | TYMP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304660-A | Pyran derivatives | RHONE-POULENC RORER S.A. (FR) | 1994-04-19 | — | — | US | disclosed |
| EP-0510050-A1 | PYRAN DERIVATIVES | Aventis Pharma S.A. (FR) | 1992-10-28 | — | — | EP | disclosed |
| WO-1991010672-A1 | PYRAN DERIVATIVES | RHONE-POULENC RORER S.A. (FR) | 1991-07-25 | — | — | WO | disclosed |
| US-4677211-A | Preparation of lactones | SANDOZ PHARMACEUTICALS CORP. (US) | 1987-06-30 | — | — | US | disclosed |
| US-4625039-A | 4-trisubstituted silyl protected hydroxy-6-oxo-tetrahydropyran-2-yl-aldehyde intermediates | SANDOZ PHARM. CORP. (US) | 1986-11-25 | — | — | US | disclosed |
| US-4474971-A | ANTICHOLESTEROL AGENTS, ATHEROSCLEROSIS | SANDOZ, INC. (US) | 1984-10-02 | — | — | US | disclosed |